In an observational study conducted in three Pediatric Intensive Care Units (PICUs) in England over a three-month period in 2019, one-sixth of patients experienced at least one adverse drug event in which they were injured by medication.
In the study published in British Journal of Clinical Pharmacology302 patients were included and 62 adverse drug events were confirmed. The estimated incidence of adverse events is 20.5 per 100 patients and most are preventable. Medicines for the central nervous system, infections and the cardiovascular system are often associated with side effects.
This multicenter study is the first of its kind in UK hospitals, and its findings could guide future remedial interventions to reduce the harm that can be avoided in this vulnerable patient population. “
Anwar A. Alghamdi, PhD, lead author, University of Manchester, UK
Reference in the magazine:
Alhamdi, AA, et al. (2021) Frequency and nature of adverse drug events in pediatric intensive care units: a prospective multicenter study. British Journal of Clinical Pharmacology. doi.org/10.1111/bcp.15150.